Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as well as possible treatment options.

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Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

While most prior studies have focused on brain-centric models of reward, some work has shown that gut-vagal signals have an effect on food-driven dopamine activity and eating behaviors. Yet it was ...

(THE CONVERSATION) Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse ...

Matt Field receives research funding from the Medical Research Council, National Institute for Health Research, Alcohol Change UK, and the Academic Forum for the Study of Gambling. He is a trustee of ...