Accessing the subarachnoid space via intrathecal needle placement can be done in nonhuman primates (NHPs) and other species to collect cerebral spinal fluid (CSF) or to deliver agents into the CSF.

Cerebrospinal fluid (CSF) is a clear bodily fluid that cushions and protects your brain and spinal cord. A CSF protein test involves taking a fluid sample from your spinal column using a needle. This ...

Although peripheral samples are far easier to obtain from humans than more invasive central ones [e.g., cerebrospinal fluid (CSF) samples], their functional significance is unknown. This is because ...