Cytovance Biologics®, a leading US-based contract development and manufacturing organization (CDMO) serving the biopharmaceutical industry, today announced the expansion of its mammalian cell culture ...
Cell line development is an essential step in the manufacture of biologics: drugs derived from living organisms, such as monoclonal antibodies, recombinant proteins and vaccines. In addition to this, ...
Over the past decade, biologics development has moved from artisanal experimentation to a data-driven, platform-based discipline. Analytical depth has improved. Process integration has matured. Yet ...
In part two of our AACR 2026 coverage, industry leaders were focussed on how the field is no longer constrained by data ...
Traditional approaches to biologics production—relying on one-size-fits-all expression vectors and empirical process optimization—have led to inefficiencies in expression, scalability, and ...
Advances in cell line engineering and microfluidic technologies offer substantial opportunities to shorten timelines in cell line development (CLD). However, as with any innovation, optimizing these ...
Luciferase-based reporter cell lines are invaluable for detecting cellular responses to signaling pathways in vitro, enabling high-throughput screening and profiling of inhibitors or activators. In ...
Cell line development continues to face technical and operational hurdles in transfection, clone selection, and media optimization. Manual screening, extended culture timelines, and fragmented data ...
Before testing new therapies in animals, researchers now have a more efficient starting point—lab-grown canine muscle cells ...
Cell line development is a crucial step in the drug discovery and development pipeline. It is essential in the manufacturing of biologics, as well as for drug screening, disease modeling and studying ...