Arthropod-borne viruses (arboviruses), such as dengue and Zika viruses, transmit widely across the globe, posing threats to ...

Modifications of the chromatin are crucial for the regulation of nearly all DNA-templated biological processes. Single-cell chromatin modification profiling can be used to assess chromatin ...

A new strategy strengthens the bond between the T cell and a target tumor cell, improving the cytotoxic function of the T cell.

The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

A Nature study identifies a previously unknown protein modification, O-2-hydroxyglutarylation, driven by the oncometabolite ...

There is an explosion of single-cell genomics profiling technologies. Although major advances have been made in measuring gene expression and DNA accessibility, assays specific to epigenetic ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...