How is it that your body with all of its specialized organs developed from a single cell? Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

New research links Wnt signalling to aggressive paediatric liver cancer and chemoresistance. Learn what this means for treatment.

Several clinical trials are testing to inhibit the LSD1 protein's ability to modify gene expression. However, the study shows that LSD1 not only affects gene expression in the way previously assumed ...

The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

Thymagen has emerged as a notable compound in contemporary peptide science due to its structural relationship to ...

On Thursday, Feb. 19, Ali May, an assistant professor at the Icahn School of Medicine at Mount Sinai presented her research ...