Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Addiction is not simply a chronic brain disease and considering it as such can limit treatment options and increase stigma, an extensive research review suggests. After decades of research, Professor ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Addiction relapse is common. Studies suggest that approximately half of all individuals who try to get sober return to heavy use, with 70 to 90 percent experiencing at least one mild to moderate slip.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Addiction is not simply a chronic brain disease and considering it as such can limit treatment options and increase stigma, an extensive research review suggests. After decades of research, Professor ...

PHILADELPHIA, PA — Researchers at Temple University Lewis Katz School of Medicine say a little-known compound could mark a major turning point in the fight against opioid addiction, showing promise in ...

Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) ...

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and decision-making, according to a study led by researchers at the Institute ...

A new study published in Translational Psychiatry provides evidence that chronic heroin addiction impairs the neural networks responsible for creative thinking. The findings indicate that the brains ...

Pathroot began in addiction treatment. We built a practical, tech-enabled platform that supports families at home with clear education, structured communication, and timely guidance.” — Carolyn ...