Processive DNA polymerases that replicate chromosomes interact with a ring-shaped clamp that encircles DNA and slides along the duplex. All sliding clamps (Escherichia coli β-clamp, T4 bacteriophage ...
The DNA polymerase III holoenzyme, which carries out chromosomal DNA replication in Escherichia coli, comprises three main parts: the catalytic core, responsible for DNA synthesis; the doughnut-shaped ...
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