A quantitative phase microscopy image of biomolecular condensates reconstituted from RNA and four distinct RNA-binding proteins. Pixel brightness is proportional to the local thickness of a condensate ...
Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...
Researchers have identified a new class of RNA molecule, called smOOPs, which support cellular phase separation, where macromolecules form biomolecular condensates that are critical for cell function.