Figure 3: CERES corrects the copy number effect and improves the specificity of CRISPR–Cas9 essentiality screens while preserving true gene dependencies. Figure 4: CERES estimates guide activity ...
Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
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