The Food and Drug Administration has approved expanded use of leucovorin calcium tablets for treating cerebral folate deficiency, a rare disorder.

Deficiency of vitamin D has been linked to issues in bone health, but recent studies are revealing a more complex relationship between this nutrient and the immune system. Emerging evidence suggests ...

Arginase deficiency is a rare autosomal recessive metabolic disorder that disrupts the final step of the urea cycle, impairing the conversion of arginine into urea and ornithine. In affected ...

The Food and Drug Administration (FDA) on Tuesday granted expanded approval to Wellcovorin for the ultra-rare disease cerebral folate deficiency (CFD) in both children and adults, the same ...

Protein C deficiency is a heritable disorder that compromises the natural anticoagulant system, thereby increasing the risk of thromboembolic events such as deep venous thrombosis, pulmonary embolism ...

For disorders that do show improvement with vitamin D supplementation, alleviating symptoms or reducing the severity or disease expression can provide improvement in patient comfort and outcomes. Thus ...

Research has associated GLP-1 medications with vitamin D deficiencies, highlighting the importance of nutrition counseling ...

A new study in mice finds that a gene therapy appears to correct a rare creatine deficiency disorder that commonly results in intellectual disabilities, problems with speech, involuntary movements and ...

Key points A 4-year-old boy presented to our urgent ophthalmology clinic for photophobia and persistent eye rubbing. He had been born at 39 weeks via Cesarean delivery, without complications. Prenatal ...

FDA worked with GSK to update Wellcovorin labelling for safe, effective use in adult and paediatric CFD-FOLR1 patients.

The FDA has approved Wellcovorin (leucovorin) for cerebral folate deficiency (CFD-FOLR1), the first-ever treatment for the rare genetic neurological condition.