Researchers say imidazolopiperazine compounds are potent against both liver and blood stages of Plasmodium parasites. Researchers are making data on a new chemical class of dual-acting antimalarial ...

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization. In each drug, a carefully concocted formula of natural and synthetic enzymes and ...

The battle to control malaria infection has been hampered by many factors, including emerging drug resistance. Now, two papers published in Nature have opened up the door to a wealth of compounds that ...

After screening a library of over 100,000 small molecules, researchers from the Broad Institute of MIT and Harvard have identified compounds that act on a novel target in the malaria parasite, ...

Malaria remains a major global health challenge and continues to impose a substantial burden across endemic regions, ...

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance. The ...