< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

One such chemical modification is cytidine acetylation (N4-acetylcytidine). Until now, the precise function of this chemical modification within cells has not been clearly understood. In particular, ...

Columbia University researchers have built a deep-learning model that predicts how CRISPR guide RNAs will behave when targeting messenger RNA inside human cells, a capability that could reshape how ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small ...

Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new ...