The urgent need for better human disease models in drug discovery is increasingly recognized, with human iPSCs playing a crucial role in developing physiologically relevant in vitro models for safer, ...

This article is based on a poster originally authored by N. Lewis, D. Cole, A. Ward, J. Trigg and N. Bevan. Researchers are increasingly using 3D models, such as organoids, to generate ...

Researchers have created the first highly mature neurons from human induced pluripotent stem cells (iPSCs), a feat that opens new opportunities for medical research and potential transplantation ...

Japanese researchers have transplanted human induced pluripotent stem cells (iPSCs) in a primate model of myocardial infarction and were able to restore heart muscle and function in monkeys. Developed ...

Human embryonic stem cells (ESCs), derived from the inner cell mass of the blastocyst before its attachment to the uterus, can differentiate into multiple cell types. Due to the ethical debate ...

From the beginning, stem cell research has presented hope for patients living with a range of diseases, from cancer to type 1 diabetes to Parkinson’s disease. The limiting factor has been the ...

A phase 1/2 study evaluating the safety and efficacy of autologous TAC T cells in subjects with claudin 18.2+ advanced solid tumors. Early phase I study of non-viral CD19/CD22/BCMA tri-targeting ...

LA JOLLA, CA---- Researchers at the Salk Institute for Biological Studies have, for the first time, taken chimpanzee and bonobo skin cells and turned them into induced pluripotent stem cells (iPSCs), ...

In a new study, researchers from Institute of Science Tokyo, Japan, have utilized bile acids as farnesoid X receptor agonists to develop unique hepatic organoids that are capable of sustained, ...