Inflammation drives TGFβ1 activation via the αvβ6 integrin-mechanotransduction pathway in human skin. Transforming growth factor β (TGFβ) is a critical regulator of skin home ...

Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells attach to one another. Now a new study by Fox Chase Cancer Center researchers ...

“Focus has been on how cells become mechanosensitive, how cell adhesion became mechanosensitive through the recruitment of mechanosensitive proteins like talin, vinculin, and also other proteins,” ...