Intrathecal chemotherapy is a form of cancer treatment in which a healthcare professional injects chemotherapy drugs into the cerebrospinal fluid (CSF). This colorless fluid surrounds the brain and ...

Panelists discuss how intrathecal delivery of onasemnogene abeparvovec in the STEER study demonstrates statistically significant motor function improvements in older patients with SMA (ages 2-18 years ...

The approval is supported by data from the STEER, Phase IIIb STRENGTH and Phase I/II STRONG studies.

Panelists discuss how emerging intrathecal gene therapy for older patients with spinal muscular atrophy (SMA) shows modest efficacy with fewer systemic adverse effects than intravenous administration, ...

Chemotherapy medications can come in many forms and types (oral, injectable, inhaled, etc.). If you need medication, the type that’s right for you will depend on how the medication works and the ...

Efficacy of systemic therapy in breast cancer with CNS metastases: “Real-world” experience. Effect of CD4+PD-1+CXCR6+ T cells on the response of immune checkpoint inhibitor therapy in brain metastases ...

THE relief of chronic severe pain in the trunk, pelvis and legs by the intrathecal injection of phenol solutions was initiated by Maher, 1 of Liverpool, and amplified by Nathan and Scott, 2 of Queen's ...

A pair of clinical data sets gives Novartis confidence in a new formulation of the company’s gene therapy Zolgensma for the treatment of older patients with spinal muscular atrophy (SMA). Among SMA ...

Baclofen (Gablofen, Lioresal, Ozobax) is a medication that treats stiff muscles and spasms, a condition called spasticity, that can happen to people with multiple sclerosis (MS) and other nerve ...

More than three years after Novartis’ plan for a speedy approval for intrathecal Zolgensma was thwarted by an FDA requirement for a pivotal phase 3 trial, the company is back with a positive readout ...