Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

Mast cell stabilizers appear to have the potential to control IRRs and possibly allow for the safe reintroduction of agalsidase in patients with Fabry disease who previously received enzyme ...

Nurse Amy Lochtie was in a meeting about infection control the first time she went into anaphylaxis — a severe reaction, usually related to an allergy, which can be life-threatening. But in her case, ...

The phase 2 Systemic Allergic Reactions to SARS-CoV-2 Vaccination trial will enroll 3400 adults aged 18 to 69 years. A clinical trial evaluating whether individuals who are highly allergic or have a ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor that ...

Mast cell precursor cells do not just cause an increase in mature mast cells during inflammation, they also play an active role in diseases like asthma, according to a new study. Mast cell precursor ...

HISTAMINE release in anaphylaxis is inhibited by low oxygen tension in guinea pig lung 1–3 and with more difficulty in rat lung 4. Conversely, at normal oxygen tension, the anaphylactic reaction is ...