The matrix metalloproteinase (MMP) family of enzymes is comprised of critically important extracellular matrix remodeling proteases whose activity has been implicated in a number of key normal and ...

Phase I Study of Paclitaxel in Combination With a Multidrug Resistance Modulator, PSC 833 (Valspodar), in Refractory Malignancies ABSTRACT: Tumor progression is a complex, multistage process by which ...

Matrix metalloproteinases are a biologically plausible and promising biomarker for rapid disease progression in ADPKD and CKD in general. Matrix metalloproteinases may predict rapid disease ...

The generation of in vitro small blood vessels mimicking the alterations of cerebral small vessel disease (CSVD) allowed a British research group to identify a way to seal leaks to treat conditions ...