Muscle-on-chip systems are three-dimensional human muscle cell bundles cultured on collagen scaffolds. A Stanford University research team sent some of these systems to the International Space Station ...

In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

Muscles are formed by the merging of many small myoblasts into larger myofibers. This fusion of mononucleated myoblasts with a single nucleus into multinucleated myofibers with multiple nuclei is an ...

Traumatic muscle injury can be associated with volumetric muscle loss (VML), often leading to permanent functional loss.

The trillions of microbes living in the human gut are increasingly recognized as important partners in human health.

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As ...

A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering ...