Human Rho GTPases (of which there are 22 members) comprise a main branch of the Ras superfamily of small GTPases and GDP/GTP-regulated molecular switches. Rho GTPases are activated by the direct ...
A library with single guide RNA (sgRNA) is packed into lentiviral particles and transduced into editor-expressing cells. The sgRNA-transduced cells are selected to generate mutant cells. Mutant cells ...
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