Captured mid-reaction, RNA polymerase reveals universal blueprint for gene transcription

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...
The Scientist

Water Molecules Play a Vital Role in Gene Transcription

EM, researchers showed that water mediates catalysis and important protein interactions for RNA polymerase II function in ...
EurekAlert!

Thermostable T7 RNA polymerase enables cleaner, higher-quality therapeutic mRNA production

Building on its success against COVID-19, mRNA technology holds promise for novel vaccines and treatments targeting various diseases. However, a critical challenge remains: current in vitro ...
Hosted on MSN

Self-replicating RNA molecule offers clues to life’s origins

Scientists have unveiled QT45, a 45-nucleotide RNA enzyme that can copy itself and its complementary strand in icy, salty conditions resembling those on early Earth. Its small size makes spontaneous ...