When clinicians contemplate the use of a new predictive technology in their practice, such as a nomogram, there is always a question of whether the new test is beneficial to their own clinical ...

Sequential hypothesis testing is a methodological framework that systematically evaluates data as it is acquired, enabling decisions to be made as soon as sufficient evidence is collected. This ...

Sequential conditional probability ratio tests (SCPRTs) provide monitoring procedures with a unique property that a decision reached at early stopping is unlikely to be reversed should the trial ...