A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

Vapourtec's Peptide-Builder, a fully automated, high-throughput benchtop peptide synthesizer, has been designed to redefine solid-phase peptide synthesis (SPPS). Compact, efficient and intuitive, it ...

Modern medicine depends on large, information-rich molecules such as peptides and oligonucleotides. These molecules carry biological instructions that can be directed toward specific disease pathways.

Cyclic peptides offer enhanced stability and bioavailability, but precise cyclization strategies and specialized synthetic techniques are required to maintain their biological activity. A recent ...

A recent video produced by Vapourtec highlights the patented automatic Variable Bed Flow Reactor (VBFR) demonstrating fully automated solid phase peptide synthesis. The process begins with swelling ...