Individual patient expanded access, sometimes termed “compassionate use,” refers to situations where access to a drug still in the development process is granted to patients on a case-by-case basis ...

Purine riboswitches have an essential role in genetic regulation of bacterial metabolism. This family includes the 2′-deoxyguanosine (dG) riboswitch, which is involved in feedback control of ...

Mammalian genomes are pervasively transcribed, with tens of thousands of unique loci producing long RNA molecules that do not serve as templates for the production of functional proteins. These RNAs, ...