New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple ...

Every thought, memory, and feeling we experience depends on trillions of tiny connection points in the brain called synapses.

For the first time, researchers have confirmed that selectively pruning certain synapses in the brain can paradoxically ...

A research team has identified a molecular mechanism that coordinates the operation of the N-methyl-D-aspartate (NMDA) glutamate receptor, which is key to regulating excitatory synapse function in the ...

Scientists used a tool called SynTrogo to edit brain circuits in mice, showing that trimming select synapses can make ...

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia. How this happens remains largely ...

The microscopic image shows a nerve cell and a magnified view of the investigated synapses. Calcium was released at these sites using a UV flash, which triggered the release of the neurotransmitter.

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song, or directions to a friend’s house become encoded in our brains? The broad answer is that our brains undergo ...