Boosting KCC2 function reduced seizures and abnormal brain activity in temporal lobe epilepsy models. Learn how this strategy could aid drug-resistant epilepsy.

Many patients suffer from epilepsy that cannot be controlled by current medications. Surgical removal of epileptogenic brain regions is effective in only about half of cases, and not all patients are ...

New research by the Human Brain Project has found that in the brains of patients with epilepsy, changes in large scale neuronal activations can be detected in the brain's resting state activity, even ...

In a retrospective cohort, a clinical heuristic composed of eight binary variables helped identify which patients with medial temporal lobe epilepsy (MTLE) were best suited for stereotactic laser ...

For patients with mesial temporal lobe epilepsy (MTLE) that can't be controlled by medications, a minimally invasive laser procedure performed under MRI guidance provides a safe and effective ...

December 5, 2008 — A new analysis using a simulation model suggests that, on average, anterior temporal-lobe resection should provide substantial gains both in life expectancy and quality of life for ...

The present study was designed to evaluate the genetic mechanisms in patients with focal epileptiform discharges in the mid-temporal or central regions, an electroencephalographic abnormality of high ...

The temporal lobe is part of the cerebral cortex. It plays a role in memory, enables people to process sound and vision, and is crucial for recognizing objects and language. Dysfunction in the ...

A 23 year-old woman presented for evaluation of intractable seizures. Her seizures would typically start with the perception of an odd smell followed by a staring spell. She would remain awake but ...