Researchers have found a new example of how the machinery that controls the transcription of DNA to messenger RNA (mRNA) is tailored to specific cells or genes. September 14, 2001 -- Researchers have ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life. But the inner workings of this ...

Each gene in our DNA has a beginning and an end. Defining the gene's extremities properly is crucial in producing functional protein. Much research has been done to identify what determines when, ...

Researchers found that in the model organism E. coli, the fidelity of transcribing DNA comes at the expense of DNA repair. A groundbreaking and surprising discovery provides a major conceptual change ...

All cells in an organism contain identical DNA sequence. What determines the identity and function of individual cells and tissues, is the set of genes that will be active in a given place, at a given ...

Transcription and replication occur at high frequency in cells. As they share the same DNA template, a high incidence of encounters is expected between the transcription and replication machineries, ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor ...