Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on ...

Despite the gazillions of hours (and possibly as many dollars) spent searching for a cure for cancer, none has emerged. This is primarily because every tumor has a different mutational profile and ...

Genetic abnormalities are a hallmark of cancer. Hereby, cytogenetic aberrations and small-scale abnormalities, such as single-nucleotide variations and insertion/deletion mutations, have emerged as ...

Researchers discover unexpected patterns in mutation risks across individuals, uncovering 13 distinct genomic patterns. The study provides crucial insights into cancer evolution, identifying the genes ...

Among patients with non–small-cell lung cancer (NSCLC), data on intratumor heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. We wanted to prospectively ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...

When a species lives in two distinct types of habitats, individuals with traits better suited to each habitat will thrive and reproduce, naturally selecting descendants with those traits.

Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises - shedding new light on mutation processes that ...