Overall structure of the iRhom2–ADAM17 zymogen complex. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2500732122 Two key protein structures in the body are being ...

Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

Researchers have captured the assembly of the NLRP3 inflammasome inside intact human cells for the first time. These ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...

Particles (encircled in green) are spaced at a distance from the noise surrounding the nanobeads (purple), which would otherwise obscure them. Sample loss has been a persistent problem in cryo-EM, a ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

A Rochester Institute of Technology student developed a tool that can help scientists visualize molecular motion and dynamics of proteins using virtual reality headsets. Kyle Diller, a fifth-year ...

Predicting protein structure was, until recently, a difficult and frustratingly slow process. The advent of the prediction algorithm AlphaFold changed everything. Now, scientists can rapidly link a ...