Case-control studies remain a cornerstone of observational epidemiology, enabling efficient investigation of associations between exposures and rare or costly outcomes. At their heart lies the careful ...

Jay Bhattacharya dismissed the test-negative design as 'crap.' The biostatistics literature tells a different story.

As biomarker studies employ increasingly complex and expensive genomics and other correlative methods, it is increasingly important to rigorously design these studies and analyze the downstream ...

Changes in the vaccine advisory process in the United States have disrupted immunization guidance, which reinforces the need for independent evidence review to inform decisions regarding immunization ...

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...

Objectives: Case management is commonly used by health plans to attempt to improve the care received by their members who have complex needs, such as those who undergo transplantation. There are few ...