The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists ...

Living cells are sustained by countless chemical reactions that must be carefully regulated to maintain internal order and ...

Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond ...

For much of nutrition science history, trace minerals were discussed almost exclusively in the context of deficiency diseases ...

Ten years ago, researchers obtained the first crystal structure of Dicer, a key enzyme in a biological process called RNA interference (RNAi). In RNAi, a process also known as gene silencing, a short ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists have investigated a multi-enzyme complex that plays an essential role in metabolism ...

David Cantu and Tin Nguyen have received a 3-year, $599,999 grant from the National Science Foundation’s Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Program to support the creation ...