Germ cell development and oogenesis represent central processes in the reproduction of invertebrates, exhibiting remarkable diversity in cellular architecture, developmental mechanisms and functional ...

Can fragments of tumor DNA in the blood predict whether chemotherapy will be effective? Researchers at the Princess Máxima Center investigated this question together with experts from Italy and ...

Non-seminoma is a type of germ-cell testicular cancer. Treatment may include surgery to remove a testicle, lymph node removal, and chemotherapy. Most cases of testicular cancer develop from germ cells ...

Innovations in the care of adolescent and young adult (AYA) germ cell tumors (GCTs) are needed for one of the most common AYA cancers for which treatment has not significantly changed for several ...

In this phase 2 study, researchers aimed to evaluate the effectiveness of tyrosine kinase inhibition in relapsed or ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Tsukuba, Japan—Animal organs are enclosed by a specialized epithelial layer. Epithelial cells typically exhibit apicobasal polarity: their apical surfaces contact other cells or the environment, ...