Conditioning regimen-dependent disposition of cyclophosphamide and hydroxycyclophosphamide in human marrow transplantation patients. From February 1991 to January 1993, 61 patients with a range of ...

Amsterdam, the Netherlands - The arrival of multiple new drugs for treating rheumatoid arthritis (RA) presents rheumatologists with the challenge of learning how best to combine these agents. An in ...

Since the 1940s, inhibitors of thymidylate biosynthesis have remained among the most effective chemotherapies used in the treatment of cancer The enzyme thymidylate synthase (TS) is a key metabolic ...

The novel beta-coronavirus virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronaviruses, in general, alter the host's cellular metabolism to support massive production of ~30 ...

An international paper on folate biomarkers is part of an initiative to provide evidence-based guidance for the global nutrition and public health community. The comprehensive study on folate, an ...