Kupando has raised an additional €10M in Series A financing, bringing its total to €23M, to fund Phase 1b trials of KUP101.

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production ...

Scientists discover how innate immunity envelops bacteria. The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

The innate immune system serves as the body's first line of defence, rapidly detecting and responding to external pathogens and internal damage. Recent advances in the field have highlighted the ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Caenorhabditis elegans has emerged as a robust model for dissecting the fundamental mechanisms of innate immunity and host–pathogen interactions. Despite lacking an adaptive immune system, C. elegans ...

The immune system has two separate responses, which are orchestrated to optimize protection against pathogens. The first response is known as innate immuni | Immunology ...