At the recent American Society of Hematology annual meeting, researchers presented preclinical data examining how transdifferentiation between hematopoietic lineages -- driven by LMO2 expression and ...

Cellular reprogramming is like the fairytale of spinning straw into gold: you take an abundant, mundane cell type, dose it with a cocktail of chemicals, and voilà—now you have an unlimited supply of ...

How can a specialized cell change its identity? A research team investigated a 100% effective natural example of this phenomenon, which is called transdifferentiation. This process, by which some ...

This news release is available in Spanish. All it takes is one molecule to reprogram an antibody-producing B cell into a scavenging macrophage. This transformation is possible, new evidence shows, ...

We report on the case of a 41-year-old man with a 2.1-cm primary malignant melanoma of the skin, located on the crown of the head. The tumor was stage pT4 (with invasion of contiguous structures), ...

Tsukuba, Japan—Vascular diseases such as atherosclerosis, pulmonary hypertension, and cardiac fibrosis are associated with a reorganization of the structure of blood vessels. Researchers led by the ...

In mammals, sounds are perceived through mechanosensory hair cells located within the sensory epithelium of the cochlea (the organ of Corti). Hair cells produced during development are postmitotic and ...

Direct reprogramming or Transdifferentiation is a way of inducing changes in the cell type from one lineage into another lineage, bypassing pluripotency. This approach is an innovative choice to ...

The ability to reliably convert the phenotype of one cell to another would be a game-changer for regenerative medicine. However, predicting the reprogramming factors necessary to induce cell ...