Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource
Research in gene therapy involving genome-integrating vectors now often includes analysis of vector integration sites across the genome using methods such as ligation-mediated PCR (LM-PCR) or linear ...
Mutant MGMT genes encoding O 6 BG-resistant proteins have been included in retroviral vectors as chemoselectable markers for transduced cells. 4, 5 Although MGMT-mediated chemoselection can ...
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