Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are …

Aug 29, 2025 · Treatment with digitoxin led to a lower combined risk of death from any cause or hospital admission for worsening heart failure than placebo among patients with heart failure and reduced …

Jul 8, 2007 · Digitoxin is a cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.

Mar 3, 2026 · "Based on our findings, digitoxin represents an additional option for patients with HFrEF, particularly those with atrial fibrillation, higher heart rates, low blood pressure or impaired kidney …

Sep 16, 2025 · Although digitoxin may offer pharmacokinetic advantages in advanced chronic kidney disease or with fluctuating renal function, current evidence is insufficient to support a …

Digitoxin is a lipid-soluble cardiac glycoside that is used to treat congestive heart failure, arrhythmias, and heart failure. It works by blocking the sodium-potassium ATPase in the plasma membrane, …

Oct 8, 2025 · Digitoxin could offer an option for patients with advanced HFrEF, particularly those with renal impairment. Regulatory and guideline bodies (NICE, MHRA) will need to review the evidence …

Aug 29, 2025 · Treatment with digitoxin led to a lower combined risk of death from any cause or hospital admission for worsening heart failure than placebo among patients with heart failure and reduced …

Aug 29, 2025 · Digitoxin reduced the risk of a composite of all-cause death and hospital admission for worsening heart failure, suggesting digitoxin may represent an additional treatment to current …

Aug 29, 2025 · Digitoxin is considered a safer cardiac glycoside than digoxin, with serum concentrations remaining stable without dose adjustments. In the DIG trial, digoxin failed to reduce the risk of all …